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Fallout 76 Diseases

FO76 publicteam xpd.pngFor an overview, see diseases and viruses.
Icon vaulttec.png Fallout 76 Overview Icon vaulttec.png
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Each Disease has unique penalties. Use Disease Cures, Antibiotics, or wait until the Disease expires on its own.— In-game notification

Diseases are a type of negative condition in Fallout 76.

Gameplay

When the player character consumes unclean food and liquid, there is a chance of acquiring a disease. Exposure to the elements, such as sleeping on floor mattresses, swimming in contaminated water or breathing toxic air, can also cause disease. They may also be contracted from contact with diseased creatures. Similar to mutations, diseases have a 30-minute cooldown for catching another disease or 45 minutes for the same disease. Leaving the server resets this cooldown so that another disease can immediately be obtained upon joining a different server.

Prevention

Fo76 Disease icon.png

Diseases can be avoided by cooking food, eating pre-War packaged food and drinking boiled or purified water. Sleeping on raised mattresses will never grant a disease, while sleeping on a floor mattress may inflict one. Avoid physical contact with diseased (Disease) creatures, as each melee attack has a chance to inflict disease.

They may also be avoided by maintaining a character's food and water needs, as each increases the resistance of disease by 25%, or by 35% with the perk Rejuvenated. Taking antibiotics or consuming certain food and drink also temporarily increases disease resistance, but using RadAway will temporarily reduce disease resistance by 50%.

The perks Iron Stomach and Thirst Quencher greatly reduce the chance of disease from consumed food and liquid, respectively, while the perk Vaccinated protects against diseased creatures. The mutations herbivore and carnivore will grant immunity to disease when eating raw and spoiled plants or meat, respectively.

Treatment

All diseases will naturally expire over time. A single disease can be cured early by using a disease cure or antibiotics, drinking from the sulfur water fountain at a white gazebo near the Whitespring Golf Club, or by entering the constructible Sympto-Matic. The C.A.M.P. ally Solomon Hardy will cure diseases for the C.A.M.P. owner.

Variants

Image Name Caused By Duration Effects Form ID
Infobox.webp Blood Worms Inflicted by a diseased radroach. 15 min Take 25% more damage 003DF043
Infobox.webp Bone Worms Inflicted by a diseased Mole Rat or radrat, or stepping on traps such as a punji board. 15 min Take 50% more limb damage. 00008881
Infobox.webp Buzz Brain Inflicted by a diseased ant. 60 min INT -2 004C6B34
Infobox.webp Dysentery Eat raw carrots, spoiled meat, swim in toxic water. 15 min Periodic water loss. 00284956
0028495A
Infobox.webp Fever Claw Inflicted by a diseased mirelurk hunter. 15 min Negative 25% Damage with Melee Weapons. 004C6B48
Infobox.webp Flap Limb Inflicted by a diseased mirelurk. 60 min STR -2 004C6B1F
Infobox.webp Glowing Pustules Inflicted by a diseased glowing one or radstag. 15 min Bleed radiation from wounds when hit. 004B0095
004B0096
Infobox.webp Heat Flashes Inflicted by a diseased honey beast. 45 min END -2 004C6B2A
Infobox.webp Jelly Fingers Inflicted by a diseased stingwing. 15 min Plus 50% Ranged VATS AP Cost. 003C75C4
Infobox.webp Lock Joint Inflicted by a diseased wolf. 15 min Melee AP cost +50%. 003C75BE
Infobox.webp Needle Spine Inflicted by a diseased angler. 15 min -10 Carry Capacity. 003C75B8
Infobox.webp Parasites 15 min Periodic food loss. 00112E6D
Infobox.webp Rad Worms Inflicted by any feral ghoul or a diseased mutant hound. 15 min Take 50% more radiation damage. 003DF041
Infobox.webp Rattle Hands Inflicted by a diseased mirelurk king. 45 min Reduced 25% damage with ranged weapons. 004C6B4F
Infobox.webp Shell Shock Inflicted by a diseased mongrel or Deathclaw. 45 min Action Point drain from wounds. 004B009C
Infobox.webp Sludge Lung Inflicted by a diseased wendigo, or exposure to toxic air without wearing a gas mask, Assault Gas Mask or spacesuit helmet. 60 min Max AP -50, AP regen -50. 0018EF92
Infobox.webp Snot Ear Inflicted by a diseased Snallygaster or gulper. 15 min PER -2. 004C6B25
Infobox.webp Swamp Gas Inflicted by a diseased bloatfly. 15 min CHR -2. 004C6B2F
Infobox.webp Swamp Itch Sleep in a sleeping bag/mattress on the ground. 15 min AGI -2. 003CD03B
Infobox.webp The Blight Inflicted by a diseased Scorchbeast, Grafton Monster, mega sloth or mirelurk queen. 30 min Negative 1 to all S.P.E.C.I.A.L stats. 004C6B3E
Infobox.webp The Woopsies Inflicted by a diseased mirelurk spawn. 15 min LCK -2. 004C6B39
Infobox.webp Weeping Sores Inflicted by diseased radscorpions or Yao Guai (Fallout 76)

Notes

  • As of patch 1.2.1.18, the player character must be level 15 or higher to acquire a disease.
  • As of patch 1.5.3.10, the penalty to having Fever Claw was changed from ranged weapons to melee weapons.

Appearances

Diseases appear in Fallout 76.

Bugs

PCPC Xbox OneXbox One Playstation 4Playstation 4 The Plague Walker mutation does not prevent the time-based expiration of diseases, which it claims to do. [Patched]; confirmed to be a description error in January 26, 2021 patch.