Poison Resistance

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Derived statistic
Poison Resistance
Information
Modifies	Poison damage reduction, chance to get poisoned
Affected By	Endurance
Base Value	Endurance * 5
Perks	Snakeater, Vault City Inoculations
Traits	Fast Metabolism
Modifies	Poison damage reduction, chance to get poisoned
Affected By	Endurance
Base Value	(Endurance - 1) * 5
Perks	Cyborg, Survival Expert Tribal Wisdom Heartless, Cardiac Arrest

“Reduces poison damage by this amount.”— Fallout game description

Poison Resistance is derived statistic in Fallout, Fallout 2, Fallout Tactics, Fallout 3, Fallout: New Vegas, Fallout 4 and Fallout 76.

This statistic reduces poison damage by a percentage as well as the chance to get poisoned. In Fallout 3 and Fallout: New Vegas, this statistic is hidden.

Fallout, Fallout 2, Fallout Tactics

${\text{Initial Level}}={\text{Endurance}}\times 5$

• The Fast Metabolism trait sets initial Poison Resistance to 0.
• The Snakeater perk increases Poison Resistance by 25% per rank.
• The Vault City Inoculations perk increases Poison Resistance by 10%.

Notes

• The average NPC has a 25% Poison Resistance.
• In Fallout, Poison Resistance is capped at 100%, although it cannot be raised past 75%.
• In Fallout 2, it is capped at 95%.

Fallout 3

Poison Resistance is also present in Fallout 3. It plays a much smaller part than in the previous games since only a few enemies (Radscorpions chief among them) use poison, and poison effects tend to be weak.

${\text{Initial Level}}\%=({\text{Endurance}}-1)\times 5$

Example: A starting Endurance of 5.

$(5-1)\times 5=20\%~{\text{Poison resistance}}$

• The Cyborg perk can increase resistance by +10%.
• The Survival Expert perk can add between an additional +2% to +6%.

Fallout: New Vegas

Fallout: New Vegas uses the same equation as Fallout 3, but Poison Resistance has much more use: there are Cazadores, Bark Scorpions, Nightstalkers, and weapon poisons, all in addition to radscorpions. In Lonesome Road, there are also venomous tunnelers. Moreover, poison in Fallout: New Vegas is generally much more lethal.

Honest Hearts perks

• Tribal Wisdom increases Poison Resistance by 25%.

Old World Blues perks

• Mile in Their Shoes - after consuming the Nightstalker Squeezin's, Poison Resistance is increased by 5%.
• Cardiac Arrest increases Poison Resistance by 50%.
• Heartless makes the player character immune to poisoning.

Items and consumables

• Gecko-backed leather armor, Gecko-backed metal armor and variants (+15).
• Wasteland tequila (+5, affected by Survival) and large wasteland tequila.
• Snakebite Tourniquet cures poison and +85 resistance (30s).
• Antivenom, Datura Antivenom and Fiery purgative cure poisoning.
• Hazmat suit (+85 resistance).
• Blood Shield (+50 up to +85 depending on the player character's Medicine).

Fallout 4

Poison Resistance is not a derived statistic in Fallout 4. Acquiring it is only possible via four methods:

• Astoundingly Awesome Tales #5: Grants +5 Poison Resistance.
• Legendary Armor pieces with the Poisoner's modifier: Grants +25 Poison Resistance. A maximum of 5 pieces can be worn at once, totaling +125 Poison Resistance.
• Med-X: Temporarily provides +250 Poison Resistance.
• Tunnel Snakes outfit: Grants +10 Poison Resistance.

Poison damage inflicted to the player stacks and it is usually accompanied by a debuff to S.P.E.C.I.A.L. attributes. Almost all bugs inflict poison damage, some like radscorpions and the mirelurk queen can be quite dangerous.

Bugs

• PC Playstation 4 Xbox One If the player boosts their Poison Resistance while already poisoned the S.P.E.C.I.A.L. debuff applied with the poison becomes permanent.

Fallout 76

Poison Resistance is not a derived statistic in Fallout 76 as it can be directly influenced by the player; it is not derived from any other statistic and is not a function of any other value. Players can modify their own Poison Resistance in the same manner as other resistances, through armor, perk cards, or consumables. Poison damage comes from a small variety of enemies and weapons, such as the scorchbeast queen and bug grenade.

Poison Resistance

Poison Resistance can be acquired via the following:

• Poisoner's armor: +25 Poison Resistance (per piece).
• Funky Duds legendary perk: +50/100/150/200 Poison Resistance.
• Tato soup¹: +10 Poison Resistance.
• Cave fungus soup¹: +10 Poison Resistance.
• Grognak the Barbarian issue #3²: +15 Poison Resistance.
• Astoundingly Awesome Tales issue #9²: +15 Poison Resistance.

¹² These share the same buff and as a result, cannot be stacked with each other.