“My boys are huntin' 'Lurks. Finest meat you can get, and it don't move around in your stomach like Mole Rat does. Right dangerous, those things. Just as soon take your head off as look at'cha. Watch yourself out here. They're all over.”— Grandma Sparkle
“The trick to tackling a Mirelurk is not to aim at the well-protected torso, but hit the small face, or failing that, the pincer arms or legs. Mines are a great way to slow them down. Beware the King as his shriek attack ignores all armor; sidestep the shriek shockwave if you can. Also note that Mirelurk Meat is the tastiest treat around!”— Fallout 3 Official Game Guide/Faction profiles
- Mirelurk meat, especially the soft shell variety, grants HP replenishment. Grandma Sparkle remarks that mirelurk meat is "the best meat you can get out here". A mirelurk cakes recipe is found in a fridge in the Anchorage War Memorial, but it cannot be made by the player character.
- Mirelurks cannot attack while swimming.
- In Vault 92, white noise instantly kills them.
- A Brotherhood initiate can be found burning a dead mirelurk with a Flamer near the Jefferson Memorial after Project Purity becomes operational. He remarks that the creatures are dying in the new pure water and appear to require contaminated water to live. There is also a Brotherhood Knight patrolling the steel deck, who mentions that they are encouraged to take potshots at the dying mirelurks.
- With Broken Steel installed and the main missions completed, mirelurk hunter corpses found in the Tidal Basin will be labeled as regular mirelurks.
Mirelurks appear in Fallout 3.
- Mirelurks killed in water will often flip over on their fronts and twitch. This is purely a graphical glitch related to their wireframe. Sometimes they will twitch so much they fall right through the floor, or become trapped in walls and doors while constantly playing a collision noise that can alert other enemies.
- Sometimes when mirelurks are killed on land, body parts will sink into the textures on the floor, as much as half their body, and the remaining parts will flail and bounce.
Mirelurks in the Anchorage Memorial
Two swamplurks found dead near the Sacred Bog's center
A pile of Mirelurk Eggs
Concept art by Adam Adamowicz