The Adirondacks are a mentioned only location.
After Garrahan Mining Company lost the Man vs. Machine contest to Hornwright Industrial and their Auto-Miners, Vivian Garrahan had to make some very difficult decisions regarding the future of her company. They had invested heavily in the Excavator power armor, and with the company now in a precarious financial situation, Vivian considered moving operations to the Adirondacks, or shutting down the company entirely. Instead, she would begin automating the company, causing a new round of riots across Appalachia.
The Adirondacks are mentioned only in Fallout 76.