Kill the Shi Emperor

If you choose to be a Hubologist and follow their teachings, the assasination of the Shi Emperor is the First Quest given by AHS-9, the Hub Leader (dressed with a tuxedo) or AHS-7, the recruiter (dressed with a dark purple tunic).

You have to go to the Shi Temple (west of San Francisco) and kill the Emperor (who actually is a supercomputer that the Emperor's "advisor" uses to direct the Shi) by formatting "him".

This is a very evil quest, because everyone in the city will attack you, so you'll have to kill everyone...