Fisto!

 is a unique variant of the Power Fist that deals higher base damage than the standard model.

Location
Fisto! can be found on the upper area of the Derelict Power Plant right across from MDPL-13 Power Station next to a computer on a desk. This is northwest of Minefield. Inside the power plant are multiple Feral Ghouls, and two Glowing Ones. Note: The Ghoul Mask can be worn to avoid the Ghouls and make them not attack you. However, if you kill one it will make the others hostile even if you still have the mask on.

Trivia

 * The Fisto! is a reference to the He-Man and the Masters of the Universe character Fisto.
 * The Fisto! (and the basic Power Fist) bear some resemblance to Hellboy's "Right Hand of Doom". Fittingly, the actor Ron Perlman, the voice of the narrator in Fallout 1, Fallout 2, and Fallout 3 played Hellboy in the two movie adaptions of the comic books.

YouTube Videos
Fallout 3 Unique Weapon: Fisto!! y1p7nxwC5Ek

Related videos:
 * | How to get the Fisto!