Nuclear Family

Nuclear Family is the final Institute main quest and achievement/trophy in Fallout 4.

Quick walkthrough
Talk to Father.

Speak with Father
Return to the Institute to speak with Father and listen to his final words before he dies of terminal cancer. Shown next are glimpses of the player character's life prior to the war and their experiences since.

This short quest completes the path through the main story. The player character may continue their adventures in the Commonwealth afterward.