High Times

High Times is a side quest in Fallout: New Vegas.

Detailed walkthrough
Speak to Julie Farkas. She is a doctor with the Followers of the Apocalypse at The Old Mormon Fort. During dialogue with the Courier, Julie mentions two men who are addicted and asks the player character to find Bill Ronte and Jacob Hoff and help them. Agreeing will begin the quest.

Bill Ronte is located in Freeside, in an abandoned house located across the street from the Silver Rush. He will tell you about how only Dixon's alcohol will calm his addiction, and that the withdrawal symptoms are too strong to quit.

Jacob Hoff is found in the crumbled building across from Mick & Ralph's. He is sitting on the ground directly forward as you enter the building. He will say he feels young and strong when he takes Dixon's chems, and that it's too hard to quit.

After speaking to at least one of the addicts, speak with Dixon (the source of the addicts' problems). He is found outside of Mick and Ralph's store, near where Jacob is found. After a Speech check of 35, Dixon will agree to leave the addicts alone. The Courier can also bribe Dixon with 300 caps or kill him. A Speech option to attack him makes him aggressive, so killing him will not affect Karma. With the Black Widow perk, the Courier can also convince him to leave Bill and Jacob alone. Then they can approach the men and help them deal with their problem.

Jacob will ask for ten doses of Fixer to help him clean up, but passing a Science check of 50 allows a combination of Fixer, Psycho, and Buffout instead, or passing a Speech check of 50 will result in Jacob cleaning up on his own.

Bill can be convinced to head to the Old Mormon Fort with a Speech check of 50. However, if the player character tells him "You won't be seeing Dixon anymore," a dialogue option involving detoxing with two doses of Fixer, Whiskey, and RadAway will appear. A Science 50 check can be passed to skip the RadAway. The 50 Speech check to go to the fort can then be used to gain experience from both skill checks.

If the player character can't pass the Science and Speech checks, Fixer can sometimes be purchased from Dixon or from the bartender in Brimstone, the bar/strip club located in Gomorrah.

Also, take note that several Freeside thugs may spawn after sending each addict to the Mormon Fort; letting the addicts die may negatively impact the rewards of the quest.

After speaking with both men, return to Julie Farkas at the Old Mormon Fort. She will thank the Courier for helping the men and offer them a discount on her services. They will also be able to get one free stimpak, Fixer, or RadAway every 24 game hours from Julie. This will finish the quest.

Behind the scenes
When a person takes drugs to get to a satisfying point, it gives them a "high." That is most likely why the quest is called High Times.