Hole in the Wall

Hole in the Wall is a quest in Fallout 4.

Quick walkthrough
The Sole Survivor is tasked with getting the cure from Curie in the secret part of Vault 81. This part of the vault is dangerous, as it contains turrets and infected mole rats. If the player character is bitten by a mole rat, the character will suffer a health penalty.

Detailed walkthrough
After talking with Erin during the Here Kitty, Kitty quest *and* donating blood to Dr. Forsythe, leave the vault for 24 hours or more. Austin will have been added to the vault hospital. Speaking with Dr. Penske begins Hole in the Wall. The quest may not start unless having spoken to Dr. Penske about trying her new strain of Mutfruit.

Austin, a boy from Vault 81 was bitten by a mole rat when wandering in the secret lower level of Vault 81 and subsequently falls ill. The player character must follow Bobby De Luca to the secret entrance located in the reactor room. He is asked to go into that part of the vault and find a cure. During the investigation, the true purpose of Vault 81 is discovered. The password to the locked terminal is next to the research comm terminal in the subsequent room, after this the player finds the cure; however, there is only one dose left. The player character must decide - give it to the boy (who is in a coma now) or use it on themself, if during the quest the player character also was infected with the molerat disease.

Options

 * Give Austin the cure: If the player character gives the cure to the boy, they receive rewards including the syringer rifle and a room in Vault 81. As a side effect, the player character keeps the disease permanently (-10 max HP).
 * Use the cure on themselves: If one uses the Vault 81 cure on his/herself to cure the molerat disease, Austin dies and everyone in Vault 81 blames the Survivor.

Bugs

 * The cure can be used on both the player character and Austin if, during the conversation with the doctor, the player tells him to use the cure on Austin then quickly backs away and uses the cure on themself before it is removed from the player's inventory. Note that you have to use the cure after Dr. Forsythe begins responding, otherwise you will trigger the dialog for having used it yourself.
 * If leaving the vault before Bobby opens the secret door, he will have gone into the secret vault with the secret door still being closed, making it impossible to finish the quest.
 * If leaving the hidden vault with the security key holotape in the inventory one will no longer be able to access the locked door to get the cure as the terminal which opens it will not register that the Sole Survivor has the holotape anymore. Sometimes this will happen even if one does not leave the vault, and progress will become impossible without cheating.