A Spoonful of Whiskey

 is a Fallout 3 quest that is added to the game with the Point Lookout add-on.

Walkthrough
Marguerite will try and convince you that she is sick, and she needs these items to get better. With medicine and speech she will admit she makes moonshine and ask you to gather these items for caps as well as a share of the moonshine.

You need
 * 3 yeast.
 * 6 fission batteries.
 * Either 10 refined punga fruit or 20 wild punga fruit.

It is a wise idea to travel light and find a way to get the fission batteries and punga fruit to Marguerite. The required items will total a massive 70 lbs., or 80 if you're carrying wild punga; if you're also carrying the required 12 pounds of yeast, that's 82 or even 92 pounds on top of your other equipment.

It is possible to bring the items per batch to Marguerite; this may be a more weight-efficient way of completing this quest. You can also drop the items in her kitchen and retrieve them later once you have them all.

A good place to find both the yeast and the fission batteries is Blackhall Manor (if you haven't already taken the items). The yeast is all around upstairs and down and the fission batteries are upstairs. Look everywhere, there are 6. There are also another six fission batteries and also 3 yeast below the batteries in the Calvert Mansion panic room if the house has been destroyed. Yeast and batteries can also be found in the Trapper's Shack or the all 6 fission batteries and 3 yeast can be found at Turtledove Detention Camp. Exactly 6 fission batteries and 3 yeast can be found in Desmond's panic room. This is found where the mansion was (must have completed Thought Control first). You can get the refined punga fruit from the Ark & Dove Cathedral after you have completed the Walking with Spirits quest; yeast is also plentiful in the Cathedral. If you haven't completed Walking with Spirits then you can get 25 wild punga fruit at Grower's Shack. If you want to do the quest fast you can buy 20 wild punga fruit from Tobar at the Point Lookout Pier. (Not recommended for you won't make a very good profit.)

Haley usually stocks multiple fission batteries.

Reward
You will receive 300 caps and six moonshine. You can also repair her still for good karma or an additional 100 caps (200 with a speech check).

Behind the scenes
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 * The title of this quest may refer to the practice of using small quantities of high-proof spirits as a 'cure-all' folk remedy, especially in and around Appalachia where the production of home-brewed grain alcohols have been a part of the local culture since the arrival of European settlers in America.
 * The practice of adding battery acid to moonshine is intended to make it taste more alcoholic than it actually is. It does not actually improve the finished product, and can, in fact, make it dangerous to consume.
 * The original draft of this quest had the player bringing in an additional 24 bottles of purified water to help brew the moonshine. This can be seen on the GECK's list of quest entries.