Desdemona

Desdemona is the leader of the Railroad faction.

Background
From her naturally stern demeanour it would make it hard to get to know Desdemona as a person and because she carries such a trait, very little is known about her background/past-life. If you betray the Railroad and join with the institute, Desdemona can be heard saying "I'm coming home Sam" in her final breath, to whom this may be referring to remains unclear.

Other interactions

 * If the player character does not speak to Desdemona prior to entering The Institute and accepting a mission, she shuns the player character and the Railroad questline ends.
 * If the player character is a Railroad agent but is Banished from the Institute then this also ends the Railroad questline as the player remaining undercover was vital to the plan. Desdemona encourages the player to stop the Institute with the Commonwealth Minutemen as she sees it as the best remaining option for protecting the synths.

Appearances
Desdemona appears only in Fallout 4.

Bugs

 * It is possible that during and after Glory assists the player during the quest Memory Interrupted she can either become stuck in the area or die, resulting in a halt to progress during the quest Underground Undercover when the player must warn Desdemona of the impending Brotherhood of Steel attack. This is because Glory is involved in a dialogue with the player during that event. To avoid this, the player should follow Glory out of the Malden Center Station as she can become stuck on metro gates or other objects.