Wild Card: Side Bets

Wild Card: Side Bets is a main quest in Fallout: New Vegas, given by Yes Man.

Detailed walkthrough
The factions you need to talk to are:
 * The Boomers at Nellis Air Force Base
 * The Brotherhood of Steel at Hidden Valley
 * The Great Khans at Red Rock Canyon
 * The Omertas at Gomorrah casino
 * The White Glove Society at The Ultra-Luxe casino

Each of these factions can be met in any order, and all have a quest associated with them. Upon successfully completing the associated quest, you will have the option to tell Yes Man what you have done. Alternatively, you can simply tell Yes Man to ignore the faction, thereby skipping the need to deal with them. Even if you've told Yes Man to ignore a faction, you can go back once you've earned their assistance and change your opinion of them through dialogue.

Essentially this quest is just a guidepost quest that points the player to the other factions, actually earning their aid or solving their problems requires the completion of their side-quest, which usually rewards one with reputation (reputation with the Strip for the casinos, or with the Boomers, Brotherhood, or Khans) and sometimes special benefits.

Brotherhood of Steel
Hidden Valley is a fenced in area that has an odd phenomenon during the night, dust storms concealing its bunkers. A few underground bunkers are scattered around the area. The Brotherhood bunker is on the west side of Hidden Valley toward the north end, and will be indicated by a tree stump on it. Upon entering the correct bunker, the Courier will be interrupted by two Brotherhood paladins. They will ask you to strip down to your underwear, wear an explosive collar, and to enter and meet their leader if you want to side with them (this section of the quest will not occur if the player has Veronica Santangelo as a companion).

Although the Brotherhood of Steel will not side with the Courier and Yes Man, one has three solutions:
 * Destroy Hidden Valley. Hack the self-destruction terminal on second floor (very hard), or pickpocket 3 keycards (from Elder McNamara, Head Paladin Hardin and Head Scribe Taggart) in order to generate the password for self-destruction. Once the player character has activated the self-destruct protocol, the whole base will turn hostile. Hacking the turret control console (Hard) in Paladin Ramos' room or dressing up in a Brotherhood disguise might be helpful in the escape. Alternately, killing all the bunker's inhabitants also works.
 * Convince the Brotherhood of Steel to support the NCR. Follow the NCR quest line until one reaches For the Republic, Part 2. Colonel Moore will ask the Courier to eradicate the Brotherhood, and one can negotiate with the Brotherhood Elder. Elder McNamara will, after some convincing, support the NCR to avoid conflict with them. This option will not be available if the player character helped Head Paladin Hardin to become Elder; he will not ally the Brotherhood with the NCR under any circumstances. One can report to Yes Man before or after telling Colonel Moore.
 * One can also choose to ignore the Brotherhood, provided they have met the condition of knowing enough about the faction. Letting Veronica take the Courier into the bunker allows this. Upon returning to Yes Man, he will react passive-aggressively about the player character's choice, but will allow them to continue the questline.

Boomers
To solve the Boomers' problems, the quest Volare! must be completed. This will earn their assistance in the Battle of Hoover Dam (by way of a pre-War heavy bomber) and the ability to come and go freely from Nellis. Thump-Thump, a unique grenade rifle, and ample 25mm grenade ammunition and all types of grenades can be found in the Ant Misbehavin' side quest at Nellis AFB. If one wishes to pick up the rebreather, they can acquire it from Jack and Loyal after earning Pearl's trust.

Great Khans
The Great Khans can either be convinced to help (by completing the quest Oh My Papa,) or to leave the Mojave for more fruitful areas. They can also be exterminated completely. It is also possible to get the Khans to suicide bomb Hoover Dam during the final battle through a Speech check (75) with Papa Khan after the Courier has gotten him to break the alliance with Caesar's Legion by telling him that the Great Khans have no legacy.

If the Courier does not speak to Papa Khan before killing him, they will not be able to complete the quest part with Yes Man.

White Glove Society
By dealing with the White Glove Society's problems with cannibalism during the quest Beyond the Beef, one can tell Yes Man that they fixed their problem, solving their portion of the quest.

Sometimes when one is doing this portion of the quest, Marjorie will not appear outside the Members Only area. This can be solved in two ways, both console commands: by typing and then, or by using the  command on any White Glove. Loot them, then use the console to resurrect him or her. If one loots them, they will get the key to Members Only area and a disguise so any White Gloves encounter won't attack the Courier; Marjorie should be inside.

Omertas
At the Gomorrah, one can pick up the quest How Little We Know. If the Courier chooses to aid Cachino in breaking up what the bosses have planned, then they can inform Yes Man of this fact. If one elects to help the bosses in their plan to attack the Strip, they can also tell Yes Man of this, completing that portion of Wild Card: Side Bets. Be aware that this will lower one's reputation with The Strip.

Completion
Once all the factions have either been ignored or their side-quests completed, the Courier must simply talk to Yes Man again to complete the quest.

This quest is probably the longest in the game, simply for the fact it has five components, each of which is a quest chain with between 2 and 7 parts.

Bugs

 * If you killed Mortimer before beginning this quest and Beyond the Beef, the optional part about asking him for information regarding the White Glove Society will keep showing on-screen until the quest is fulfilled.
 * Yes Man may not realize one has told him all the tribes are dealt with, which will prevent the player from finishing the quest.
 * Typing in the console then speaking wth Yes Man about the tribes should solve the problem.
 * The Yes Man monitor inside the penthouse may be missing.

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