Mentats

Mentats are a pre-war chem created by Med-Tek. These red pills increase memory related functions and speed up other mental processes. They are, of course, highly addictive.

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Fallout, Fallout 2 and Fallout Tactics
Mentats were a chem in Fallout 1, and were most useful in retard runs. They boosted intelligence, but they had addiction effects, which were very bad...

Fallout 3
Mentats return in Fallout 3, though their effects have been slightly altered to provide greater boosts to Intelligence and Perception, while omitting the increase to Charisma. They are particularly useful if the player only needs a small addition to a skill. Because Mentats boost both Intelligence and Perception, the player can gain a temporary boost to Medicine, Repair, Science, Explosives, Lockpick, and Energy Weapons skills, provided that the associated attributes are not already at maximum. Mentats can be real lifesavers when encountering locks or terminals which require slightly higher skills to unlock.

Additionally, in The National Archives, specially-flavored Mentats were given to anyone who won a trivia contest regarding the Declaration of Independence. This contest still exists in electronic form for the player to try.

The bonus flavors of Mentats provide +5 boost to a single S.P.E.C.I.A.L. attribute:
 * Berry Mentats grant a +5 to Intelligence
 * Orange Mentats grant a +5 to Perception
 * Grape Mentats grant a +5 to Charisma