Keep Your Eyes on the Prize

 is a quest in Fallout: New Vegas.

Summary
Ghost, an NCR Ranger from the Mojave Outpost, is concerned when she notices plumes of smoke rising from the reclusive town of Nipton. To add to her concern, there have been no travelers from Nipton as of late. Ghost contracts you to investigate the disturbance.

Quick Walkthrough

 * Receive the quest from Ghost at the Mojave Outpost
 * Travel to Nipton
 * Talk to/kill Vulpes Inculta or talk to Boxcars
 * Report back to Ghost

Speaking only to Boxcars will allow you to finish the quest without ever speaking to Vulpes Inculta nor entering the town hall.

Detailed walkthrough
Upon approaching the town, you are greeted by an ecstatic (if not manic) Powder Ganger who proclaims life is grand after winning the lottery. Further exploration into town reveals a row of crucified Powder Gangers along the street. At the entrance to the town hall you'll encounter a contingent of Caesar's Legion, led by Vulpes Inculta. After you have dealt with them, you may enter the Town Hall, located directly behind where the exchange with Vulpes Inculta occurred. Inside you will find several enemies and land mines, along with more details about the demise of Nipton found within the Mayors office upstairs. After exploring the town to your liking, talk again with Ranger Ghost and you will complete the mission.
 * After a brief exchange, the Legion spares your life in order for you to spread the word of their atrocities across the wasteland.
 * If you are accompanied by Boone and/or dressed as NCR, the Legion troops will instead attack you straight away.

Note: You can complete this quest by going to Nipton first before ever going to the Mojave Outpost. Talk to Ghost after talking to Rose in the bar and she will give you the quest, then you can complete it immediately by choosing the option that you have already been to Nipton.

Note: Killing all members of Caesar's Legion will yield little benefit. You will lose access to the quest Cold, Cold Heart and other assassination missions. Additionally, your reputation with Caesars Legion will become "infamous", and there is practically no loot of value on any of the corpses. Killing all members will also not add any additional award from Ghost upon completing the quest, nor will you gain any reputation with NCR.

Notable Loot

 * Worn Key immediately to the right upon entering, found on the counter of the PO box shelves.
 * Turbo (x2) within the basement level, on the coffee table.
 * Big Book of Science & Programmer's Digest located on desk in Mayor's office.
 * Future Weapons Today on the shelf behind the Mayor's desk.
 * Nuka-Cola Victory, and 10mm SMG (x2) in the locked room in Mayors office.

Bugs
If you find Vulpes Inculta later in the game (not in Nipton) and kill him, this quest will be completed even if you have never visited Nipton.