Doctor Lesko

Dr. Weston Lesko is a scientist living in Grayditch in 2277.

Background
Lesko is a somewhat befuddled and misguided scientist whose experiments on ants have proven disastrous for Grayditch. Deep inside Marigold station, he carries out his research, completely oblivious to the destruction that his fire ants have caused. He has little patience for anything beyond his scientific acumen and dismisses his failures as only temporary obstacles on the road to success. While his motivation is to save the wasteland, his methods are in fact destroying it.

Daily schedule

 * Until the quest, Those! is completed, Lesko can be found deep underground in the Marigold station. He will usually be in his laboratory outside the hatchery, or he might flee a short distance into the hatchery itself.
 * Lesko will not return to his shack until Those! is fully completed. This means one must also find a home for Bryan (or refuse to do so) and receive the experience points for this quest before Lesko will return to his shack.

Quests

 * Those!: Doctor Lesko requires the Lone Wanderer's help to regain control of his experiment. If the player has a high enough Science skill and Intelligence, an additional dialogue option appears when asking Lesko about his experiments. When the Science option is chosen (60 Science needed), Lesko reveals that he has been using FEV in his experiments. An additional dialogue option will also appear if the player has chosen the perk Entomologist, which upsets the doctor slightly.
 * Nectar Collecting for Fun and Profit: After completion of "Those!", Lesko will pay for samples of fire ant nectar. Be aware that entering Doctor Lesko's shack will be considered trespassing, even though the player might have to enter it to give him some nectar. Stay there for too long, and both the protectron and Doctor Lesko will become hostile.

Appearances
Weston Lesko appears only in Fallout 3.

Behind the scenes
In a 2019 interview, Lesko's voice actor, Mike Rosson, stated that he channeled Frank Grimes from The Simpsons for his performance.