Brian Virgil

Brian Virgil is a super mutant living in the Commonwealth in 2287. Living initially in the rocky cave, he helps the Sole Survivor find a way into the Institute.

Background
Dr. Brian Virgil was a member of the Institute at some point before 2287. He was working on an unknown project involving the Forced Evolutionary Virus and the creation of Super mutants in the bioscience division, but went rogue. He then escaped to the Glowing Sea and infected himself with a unique version of the FEV virus to survive the high levels of radiation.

Quests

 * The Glowing Sea: After heading through the Glowing Sea and talking to Virgil about needing his help, Virgil will ask to get an experimental serum that he claims will make him a human again, but isn't sure if it exists or not. The player character must agree to this if they want to complete The Glowing Sea and continue the main story line. The player character will have to go to the FEV labs in the Institute to retrieve the serum.
 * A Loose End: Unless convinced to spare him through a charisma check, Kells will order the Sole Survivor to kill Virgil.

Effects of player's actions
After getting the serum, the player character has two options:
 * They can simply give Virgil the serum, and certain companions will react differently to this choice. For example, John Hancock, Piper, Nick Valentine, Codsworth and Curie like the player's choice to cure Virgil, but Danse won't like it at all; this is due to his teachings by the Brotherhood. Strong also won't like it as he prefers being a Super Mutant and is angry with the doctor's ambitions to cure the others.
 * They can also lie to Virgil through a speech check, claiming that it wasn't there, which will prompt him to request the player character to kill him.
 * If the player character gives Virgil the serum and waits for around a week, they can go back and see that Virgil is now a normal human.
 * If the player character destroys any of Virgil's turret defenses, spotlight, or protectron prior to returning to complete the quest "The Glowing Sea", the Sole Survivor will immediately fail the quest upon re-entering rocky cave with the serum.
 * If upon first entering and leaving the Institute, even if the player does not get the serum, the player character waits before bringing the serum to Virgil for around a week, Virgil is then found completely turned hostile and quest "The Glowing Sea" will immediately fail upon re-entering rocky cave.
 * If the player character destroys the Institute, Virgil will no longer want to speak with them and will ask them to leave.

Bugs

 * There is a bug when returning the serum to Virgil that auto fails the quest and turns Virgil and his Protectron hostile if the cave is entered in power armor.
 * He will turn hostile even when returning to him once he is cured if the cave is entered in power armor.
 * This may be due to the "Targeting HUD" helmet upgrade. Simply unequip the helmet on the power armor before entering the cave.
 * Unequipped the helmet with targeting enhancement, the quest did not auto fail.
 * Virgil's super mutant form uses extremely low-resolution textures, regardless of graphics settings.

Appearances
Virgil appears only in Fallout 4.

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