Mister Sandman

Mister Sandman is a Fallout 3 Perk.
 * Requirements: Level 10, Sneak 60%
 * Ranks: 1
 * Benefit: With the Mister Sandman perk, when you’re in Sneak mode, you gain the option to silently kill any human or Ghoul while they’re sleeping. All Mister Sandman kills earn bonus XP - on normal difficulty this amounts to 50XP per kill.  Plus a successful kill earns a short jingly fanfare sound.

Mister Sandman is performed in sneak mode and by choosing "Pickpocket" on an unfortunate sleeping victim. Choosing "Pickpocket" pauses the game and brings up a menu with the options to "Murder" or "Pickpocket". A short murder animation follows with the Player looking around and slitting the victim's throat.

Mister Sandman kills can be performed on children, netting you experience, but will not kill them (as they are invincible). This can be done repeatedly. It appears that this technique does not work on patched versions of the PC game.

Possession of a knife or other bladed weapon is not necessary to perform a Mister Sandman kill, even though the kill animation shows the deed performed with a knife.

Sometimes Mister Sandman victims wake up and cry out before they die, thus alerting nearby characters (such as the group of raiders sleeping in Five Axles Rest Stop) even with 100 Sneak and Stealth Boy. Unknown if this can be fixed or avoided. Also, some victims even stand up, move around, and complain before the game decides to kill them, also alerting nearby characters.

Sometimes murdered victims will "speak" when you steal items from nearby ("That's not yours!"), though there appears to be no extra consequences for this.

Karma loss or gain from Mister Sandman kills are treated normally, i.e. murdering a good character results in loss of Karma and vice versa.