Curie

Contagions Vulnerability Robotic Infirmary Engineer, or Curie (stylized as Cvrie), is a Miss Nanny in Vault 81 appearing in Fallout 4.

Background
The state of the art Curie was designed to be the guardian of Vault 81, responsible for preserving the knowledge amassed by the Vault 81 scientists, as well as ensuring that every single one is aware of the significance of the mission undertaken within the halls of the vault. However, the current Curie is not the same robot as when she was deployed to the vault. Due to the overseer's sabotage, none of the science staff received a notification about the drill that would have allowed them to enter Vault 81 in time to carry out the experiment. However, three researchers showed up: Kenneth Collins and Jim Flint reached the vault from the Fens with the general population, while the overachiever M. Burrow was already on site. They reported to the research area and were sealed inside. This meant that the danger to the residential population still existed.

Although there were only three of them, ensuring that the generations-long research plan would die out, they had state of the art equipment, centuries' worth of supplies and the Contagions Vulnerability Robotic Infirmary Engineer (CVRIE), meaning that with even their limited manpower, they could still be a threat to the residential population. To compensate, Collins upgraded and modified Curie, from a customized Mr. Handy into a fully fledged lab assistant. He provided her with a custom personality, loading the databanks with every great body of work he had (Kant, Einstein, Born, Darwin, Curie, Faraday, Turing, Braun) to make her more life-like and human. As such, CVRIE became Curie. With her help, the work picked up the pace and quite soon, the Phase I trials began. When notified of it, Overser O. Olivette was mortified and played for time, while maintaining an aura of camaraderie, taking care to not reveal her intentions. While the mood among the three researchers remained stable thanks to Collins and Curie, they still had access to the nozzles and could release the pathogens for a Stage III trial, or worse. When a minor mishap with the mole rat population was resolved and stage II was progressing rapidly, Olivette made her decision.

The overseer personally sabotaged the delivery nozzles inside every residential quarter and room on their side of the vault. Then, when the researchers began to notice (Burrow, specifically), they disconnected the only terminal that could communicate with the science team and dumped it in the reactor chamber, near the sealed backup entrance into the science section. Sealed in the research wing, the scientists grimly continued their work, never to see the light of day again. Curie became their inheritor, watching as they fell one-by-one. Flint was killed when a mole rat named Clyde escaped his cage, while Collins and finally Burrow both died of old age. She interred them and continued the work.

Finally, in 2204, Curie finished the broad-spectrum cure that would be capable of curing every pathogen developed and analyzed in the captive mole rats. She spent the remaining time scanning the same four walls over and over again, until the Sole Survivor arrives, allowing her to exploit a loophole in her programming and escape from the bondage of the vault.

Quests

 * Hole in the Wall: Curie has access to the cure Austin needs, although she will only give it once all the nearby mole rats have been terminated.
 * Emergent Behavior: Curie wants a human body to become a better scientist.

Effects of player's actions

 * Curie can be let out from her laboratory. In addition, she can become a synth if the player character asks Doctor Amari in the Memory Den in Goodneighbor to transfer her memory into a synth body during Emergent Behavior. Dr. Amari will not give the necessary dialogue options to do so until after the completion of Dangerous Minds.
 * Curie's affinity towards the player character won't increase any further from the value 499 before the quest Emergent Behavior is completed, even if the game states that "Curie liked/loved that."
 * Upon reaching maximum affinity with Curie, she will tell the Sole Survivor about a breakthrough she has made with mutfruit that enhances the effect of stimpaks, and will give the Combat Medic perk, which heals the Sole Survivor for 100 Hit Points once a day when falling below 10% health.

Other interactions

 * Curie will occasionally give the player character stimpaks.
 * Curie will request to leave if she enters Vault 81, but her affinity level will not change.
 * Curie is a potential candidate for romance, an option that unlocks after reaching the highest level of affinity.

Appearances
Curie appears only in Fallout 4.

Behind the scenes
Curie is named after Marie Skłodowska Curie, the physicist and chemist who conducted pioneering research on radioactivity. Curie will acknowledge this when starting the quest Emergent Behavior.