The Mississippi

The Mississippi River is the largest river in North America.

Background
Before the Great War, Jesse White hosted an "Outdoor Honkytonk" outside The Rusty Pick. A flyer for the event claims Jesse's band is the "Best Honky-Tonk Band this side of the Mississippi!"

Paladin Leila Rahmani led the First Expeditionary Force across the country, from Lost Hills to Appalachia, with goals of re-establishing contact with the lost chapter of the Brotherhood. A message records there is still no contact with the group, and at one point scribes had estimated that they should have passed the Mississippi by that time.

Darius Angler mentions being the best chemist on this side of the Mississippi in part of his manifesto.

Appearances
The Mississippi River is mentioned in Fallout 3 and Fallout 76.