The New Arrivals

The New Arrivals is a main quest in the Fallout 76 add-on Wastelanders.

Quick walkthrough
Talk to the Vault 76 overseer at her home. Complete Strange Bedfellows and Here to Stay. Return to the overseer, and brew an inoculation against the Scorched Plague at Kanawha Nuka-Cola plant. Deliver the inoculation to Meg and Paige. Return to the overseer to complete the quest.

Detailed walkthrough
Upon the quest first starting, tune into the Overseer's radio station on the Pip-Boy 2000 Mark VI, where she will ask all Vault 76 residents to meet her at her new home in Sutton. Upon arriving there, the Overseer's home can be found on the hill overlooking town to the east. Upon entering, the Overseer will invite the player characters down to the basement, introducing them to her Mr. Handy assistant Davenport, and also inquiring as to if they completed their original mission from her regarding the Scorched Plague. Her reasons for asking about the inoculation are due to her concern about the new factions that have come to Appalachia. She asks the player characters to travel to Foundation at Spruce Knob to speak to the leader of the Settlers, and to talk to Rose about getting in with the Raiders at their new main settlement, The Crater, at the crashed Valiant-1 space station, so as to give them the inoculation against the Scorched Plague. If they fall victim to the Scorched and Scorchbeasts, it could be the events before Vault 76 opened all over again with the Scorched and Scorchbeast Queen able to get beyond Appalachia's borders to spread their influence due to a lack of cooperation between the various groups.

After the Overseer asks the player characters to get into the Settlers and Raiders, the quest will not advance until after completing the first quests for the Settlers and Raiders, "Here to Stay" and "Strange Bedfellows" respectively.