No Weaknesses

 is a perk added to Fallout 3 with the Broken Steel add-on.

It instantly raises all your SPECIAL stats to a minimum of 5.

If you plan on taking Almost Perfect at level 30, you likely will want to skip this perk. If you plan to take Nuclear Anomaly or any other perk at level 30, then this perk can be a good way to raise your lower SPECIAL scores.