Smuggler's End (Fallout 3)

Smuggler's End is a unique version of the AEP7 Laser Pistol. It is Elder Lyons' personal weapon and is located in his private safe in the B-Ring of the Citadel. It is found in mint condition and can be easily repaired with regular laser pistols.

It is quite possible that Elder Lyons will sleep in other beds and not his own. Also, others can be found sleeping in his bed. If this occurs it is possible that the other person found sleeping in his bed has taken Smuggler's End out of his safe and they have it on them. I noticed this when attempting to enslave a Brotherhood Scribe(doesn't seem to be possible and is of course quite dangerous), there was one in Elder Lyons bed. The Scribe's head exploded and when looting his corpse I found the weapon.