The Overseer (Vault 101)

The Overseer is the leader of Vault 101 and the father of your childhood friend, Amata. He and his wife rarely spoke to one another.

As Overseer, he is determined to keep the Vault closed to the outside world, at least for the general population of Vault 101. When James escapes, he thinks that the Vault 101 Dweller had something to do with it, so he sends his security after him/her. He orders the death of Jonas after James' escape and interrogates his own daughter during the the Vault 101 Dweller's escape. Depending on whether or not you kill him, Amata will react differently toward you.

If you do not kill him during your escape, he will tighten his grip on the citizens of Vault 101, which will result in a rebellion. Later in the game, if the player character travels near the Vault, their PipBoy 3000 will discover the Vault 101 Emergency channel where Amata was broadcasting a plea for help on a repeating loop, which then starts the Trouble on the Homefront quest.

Note
If you kill Amata's father while escaping from Vault 101, a new Overseer is named and you can still do the Trouble On The Homefront Quest.

Appearances
Just like Vault 101, the Overseer appears only in Fallout 3.