The Overseer (Vault 101)

The Overseer is the leader of Vault 101. He is determined to keep the Vault closed. When James escapes, he thinks that the Vault 101 Dweller had something to do with it, so he sends his security after him/her. Amata seems to be his daughter.

Appearances
Just like Vault 101, the Overseer appears only in Fallout 3.