Bye Bye Love

 is a quest in Fallout: New Vegas.

Quick walkthrough
This is a quest that begins in either the Gomorrah Casino or Vault 21. If the Courier goes into the courtyard Joana will begin a conversation. Passing a Medicine or Speech check will initiate dialog that will eventually have Joana talk about Cachino and Carlitos or the player can talk to Carlitos and pass a speech check to talk to him about why he left Gomorrah leading him to talk about Joana. The Courier has the option to help Joana (for free or otherwise) by finding Carlitos (located in the diner of Vault 21). After some running back and forth between Joana and Carlitos, the Courier can help Joana, Carlitos, and 2 of Joana's girls escape to Freeside. After meeting with The Beards and Carlito, 4 Omerta thugs will ambush the group. The player can either go into combat with them, or with high enough Strength, intimidate them. The first Strength check requires 8 Strength, the second 9. Another method to avoid the fight is with 85 Barter.

Behind the Scenes

 * The name of the quest might be a reference to the "Everly Brothers" song of the same name.
 * The name of the quest may also be a reference to a song by The Cars of the same name.

Bugs
Due to a glitch, Carlitos isn't appearing in the game for many people, making the quest temporarily unfinishable. To fix this on PC, simply go to the diner in the Vault 21 hotel and use the console command: player.placeleveledactoratme 11f862. This will spawn Carlitos right in front of you.

Another glitch has risen as Joana seems to disappear too after you talk with Carlitos. To fix the Joana glitch, go to the Gomorrah courtyard and us the console command: player.placeleveledactoratme 0010c6f6.
 * Another glitch can render this method useless: spawning Joana in the courtyard makes her disappear once she enters her room (since she tells the player to follow her to her room). If you spawn her inside her room, she keeps asking the player to go to her room.
 * Yet another glitch with this method which can occur and which renders this method useless is that Joana does not lead the way to her bedroom when she is supposed to. Instead, she continues to stand around doing her own thing. Attempting to engage her in conversation will only cause her to tell you to meet her in her room, but she does not budge. This bug is not experienced when Joana is not manually spawned from the console, so it seems there is some script or other NPC behavior not being attached.
 * This glitch will happen on the PS3 if you complete the How Little We Know quest before taking Joana out of the casino.

Yet another glitch exists where, after telling Joana the escape plan, she arrives in the lobby of Gomorrah - but does not follow the player. Neither do the disguised hookers waiting outside the casino; leaving to Freeside without them results in failing the quest a few hours later.

After running back and forth a few times, the dialogue option to get Joanna to run away might fail to appear. The only way around this seems to be to have a high enough speech to convince her.

Killing the bosses with Cachino during the quest How Little We Know can cause you to fail this quest.

Discovered that the "Bug" that makes either Carlitos or Joana Impossible to find only appears to happen if the quest How little we know has been completed. Thus if you completed that quest, then it seems it might be impossible to finish this quest as both main characters is missing and spawning them with a cheat command only takes you to the escape where the quest stops working when Joana wont leave the cassino.