Slave Hunt

 refers to an unmarked quest in Fallout 3.

When talking to Mei Wong in Rivet City, you can find out she is an escaped slave and therefore scared of Sister, a Slaver who is visiting the city.

You have a couple of options (other than ignoring the situation entirely):
 * Aid Sister in recapturing the slave. You receive bad karma.
 * Tell Sister that Mei Wong is an escaped slave and let her know you told him. She commits suicide and you receive bad karma.
 * Provide Mei Wong with caps, allowing her to purchase a pistol to defend herself. You receive good karma.
 * Kill Sister.

Note
If you kill Sister in his sleep with the Mister Sandman perk as to not alert Rivet City Security, there is no karma penalty, and Mei Wong will make a comment about how she is happy he is dead the next time you see her. This can be done even after you give her money to buy a gun.
 * also if you place mines around his bed while he's asleep, when he wakes up and sets off the mines it will kill him without alerting the guards

Reward

 * Karma (see above)
 * If you help Mei Wong out, she will give you the location to the Temple of the Union.