Whiskey

 is a food item found in Fallout 3 and Fallout: New Vegas.

Fallout 3
Drinking it increases Strength and Charisma by one point while lowering your intelligence by 1 point. By drinking this you run the risk of addiction, curable by doctors for a fee.

Whiskey has all the same effects as vodka and beer. It is cheaper than vodka and found more often around the Capital Wasteland.

Fallout: New Vegas
Whiskey is also a consumable item in Fallout: New Vegas

General
Whiskey provides the same base effects as in Fallout 3, increasing Charisma and Strength by 1 while reducing Intelligence by 1.

As with any food item in Fallout: New Vegas, whiskey's effects—both positive and negative—are altered by the player's Survival skill, including the DT increase provided by the Whiskey Rose perk (see below). With a Survival skill of 100 the player will receive +3 to Charisma and Strength, and -3 to Intelligence, as well as +6 to Damage Threshold if the player has the Whiskey Rose perk.

In Hardcore mode whiskey will increase the player's level of dehydration. This effect is also affected by the Survival skill, going from +25 at lower levels to +75 at 100 Survival skill.

Whiskey is used in making Party Time Mentats at Campfires.

Whiskey Rose
Whiskey Rose is a perk provided while Cass is serving as a Companion in the player's party. With this perk the penalty to Intelligence for consuming any type of alcohol is eliminated, as are the effects of alcohol addiction. However, the perk provides an additional bonus when consuming whiskey, providing a temporary 2-6 point increase (based on Survival skill level) to the player's Damage Threshold.

Variants

 * Dixon's Whiskey is a variant sold by Freeside merchant Dixon. It provides no Charisma boost and a penalty of 2 to Intelligence, and also has a high 50% addiction rate.
 * Irradiated whiskey is, as the name indicates, radioactive. It provides the same effects as whiskey with an added 10 rads.  It can be found reliably in one place: the Camp Searchlight Fire Station, three bottles located in the kitchen.  A fourth bottle may rarely be found in the refrigerator inside Hell's Motel.

Both variants do not provide any increase to Damage Threshold when the player has the Whiskey Rose perk, though their penalties to Intelligence are still negated.

Related quests
Restoring Hope: Whiskey is needed for part of Restoring Hope by helping Dr. Alex Richards at the Camp Forlorn Hope medical center. To assist Dr. Richards with three patients in the clinic, the following are needed:
 * 1st Patient: Medicine Level 35 - or - Med-X (1), surgical tubing (1), and whiskey (1).
 * 2nd Patient: Medicine Level 50 - or - Bonesaw (1), Med-X (1), and medical brace (1).
 * 3rd Patient: Medicine Level 75 - or - Med-X (1), super stimpak (1), and Tweezers (1).

Whiskey is needed for the side quest High Times. To help Bill Ronte kick his addiction, the character will need a Speech level of 50 - or a Science level of 50 and Fixer (2), and whiskey (1). If the character's Speech and Science levels are too low, then RadAway (1) will been needed as well as the Fixer (2), and whiskey (1).

Heartache by the Number: 12 whiskey can be used to convince Rose of Sharon Cassidy to sell her caravan company to Alice McLafferty.