Memory Interrupted

Memory Interrupted is a Railroad side quest in Fallout 4.

Quick walkthrough

 * 1) Speak to Desdemona
 * 2) Listen to P.A.M
 * 3) Pick a tactic (Desdemona's rerouting or Carrington's elimination of synths)
 * 4) Speak to Doctor Amari
 * 5) Pick up H2-22's holotape from the table
 * 6) Go to Malden Center
 * 7) Clear the area
 * 8) Return to Desdemona

Detailed walkthrough
Back at Railroad HQ Desdemona and Doctor Carrington can be found discussing a safe way to transport H2-22 after his memories were altered by Dr. Amari. P.A.M. will tell the group about increasing Institute activities, which will start a discussion between Desdemona and Carrington on how the Railroad should react. While Desdemona suggests rerouting the path, P.A.M. and Carrington will state that the safest way is to eliminate any synths blocking the original route.

After siding with one of the two parties, the Sole Survivor is sent to Dr. Amari to tell her about the new plan. After that conversation, Amari will tell the Sole Survivor to grab the Goodbye from H2-22 holotape from the table, which contains a personal message from H2-22 (although the conversation with Amari may take place elsewhere, "the table" in question is the round one with the red tablecloth behind Irma on the first floor stage).

The Survivor is then sent to Malden Center to eradicate any Gen 1 synths in the area. Before entering the station they run into Glory who was accidentally sent to accomplish the same mission. Together they destroy all synths, even though Glory constantly comments on the fact that she believes even Gen 1 synths should be rescued (e.g. asking if they couldn't just scare them away). It is also possible to dismiss Glory by saying you don't need any help when you first meet her outside of the station, in which case she will return to Railroad HQ, leaving you to clear the area yourself.

Afterward, the Sole Survivor should return to Desdemona for the reward.

Bugs
Desdemona does not have dialogue for reporting back to her if The Molecular Level is active and the stage where a supporting faction must be chosen has been reached, making it impossible to finish this quest until one proceeds in The Molecular Level.

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