10mm pistol

The Colt 6520 10mm autoloading pistol is a highly durable and efficient weapon.

The 6250 was developed by Colt Firearms prior to Great War and chambered for the common 10mm round. It proved to be resistant to the desert-like conditions of the post-nuclear wasteland and is a fine example of workmanship and quality construction (at least for the pre-War models, which became more scarce over time). The simple design of the gun allows it to be easily manufactured with relatively basic equipment, making it possible to be replicated in workshops in the post-nuclear world. The Colt 6520 is capable of chambering the 10mm hollow point round or the 10mm armor piercing round.

The Colt 6520's durability, reliability, and simple design makes it very popular among wasteland denizens, for whom sophisticated high maintenance weapons would be a liability to survival.

10mm Pistol is a Fallout, Fallout 2 and Fallout 3 weapon.

Fallout 3
It is know that Mr.Burke carries a silenced version this gun. It has been confirmed that the silencer can be acquired by the player, at least for this gun.

Behind the scenes
The 10mm pistol is a reference to the Hard Boiled comic books. Its plausibility as a real weapon is disputable, however there are real 10mm pistols available to civilians today. The 10mm Auto round is used for hunting.