Cerberus

Cerberus is a Mister Gutsy patrolling the ghoul city of Underworld

Daily schedule
Cerberus can be found patrolling the Underworld concourse 24/7.

Effects of player's actions
With the Robotics Expert perk, the Lone Wanderer can remove Cerberus' combat inhibitor via a dialogue option, resulting in negative Karma and Cerberus' immediate hostility to the Lone Wanderer and everyone else in Underworld.

Other interactions
If the Lone Wanderer speaks to him, they will learn that Cerberus would much rather send the ghouls "back to hell" than serve as their "guard dog," but his combat inhibitor prevents him from killing the "zombie freaks."

Appearances
Cerberus appears only in Fallout 3.

Behind the scenes
In Greek Mythology, Cerberus is a three-headed dog with snakes growing from his neck who guards Hades and the gateway to the Underworld. Cerberus the Mister Gutsy has three eyes (heads) and three arms (snakes) and guards Underworld. He even calls himself the guard dog when asked.