No Weaknesses

 is a perk added to Fallout 3 with the Broken Steel add-on.

It instantly raises all your SPECIAL stats to a minimum of 5.

If you plan on taking Almost Perfect at level 30, you likely will want to skip this perk unless it's needed to meet a stat requirement for another perk. If you plan to take Nuclear Anomaly or any other perk at level 30, then this perk can be a good way to raise your lower SPECIAL scores.