Wilhelm's Wharf

 is the name of a small wharf with a shack in Fallout 3. It is easily found by following the river SE from the Super Duper Mart.

was a small settlement located near the Potomac river in the Washington D.C. area. The old woman Sparkle resides in the area, and acts as a local trader. Her two sons hunt for Mirelurk Meat along the river. Sparkle will mention in conversation that there were three men looking for some 'do-gooder' - a hint about the Talon Company hit squads that you will encounter throughout the game, and foreshadowing the trio of Mercs you encounter as you press on through the zone (if you choose to go here early in the game). The 'do-gooder' comment is made regardless of your actual karma.

is very close to the Mirelurk nest at the Anchorage Memorial and the Tepid Sewers that Moira Brown sends you to during one of her The Wasteland Survival Guide quests. (The bridge that crosses the river has about 10+ frag mines available for collecting.)

At higher levels, the area immediately to the north of Wilhelm's Wharf features a running battle between Super Mutants and Raiders shooting at each other from opposite sides of the river. This fight usually involves 3 Raiders armed with assault rifles, and 2 Super Mutant Brutes or Super Mutant Masters armed with a minigun and a missile launcher. Both sides of combatants respawn over time.

There is a drainage culvert with a damaged grate that leads to the Hubris Comics publishing building just north of the outhouse at the north end of the wharf, near the water.

Notable Loot
Grandma Sparkle carries an assortment of Ammunition and Aid items. The wharf has a locked refrigerator outside the shack. The key to open it on Grandma Sparkle can be pick pocketed or looted off her dead body. The fridge contains a lot of food, perfect if you're planning on visiting a Super mutant infested area in the D.C. area across the River Potomac. Bad Karma is received for killing Grandma Sparkle.

You can also turn Sparkle into a slave (for Bad Karma), since she doesn't count as essential, and because she's always alone there's no threat. however by doing this you lose the key to the Refridgerator, but you get 250 caps for the slave and everything inside the house, just remember to leave her some armor for the run to Paradise Falls or you are more likely to lose her on the way. Don't worry about her in the future, she plays no important part and doesn't have much to trade, besides the Mirelurk meat.

Quests

 * Those!- You can usually pick up this quest in that area when Bryan Wilks runs to you.

Glitch
The writer of the glitch article discovered a glitch when traveling to Wilhem's Wharf. After clearing out all raiders from Super-Duper Mart, he decided to do some exploring. He walked inside the building in the Wharf to find Grandma Sparkle dead on the floor. As soon as he left the building, he started getting shot by some random Raider.