Keep Your Eyes on the Prize

 is a quest in Fallout: New Vegas.

Quick walkthrough
Ghost, an NCR Ranger (sniper specialty) from the Mojave Outpost, is concerned when she notices plumes of smoke rising from the reclusive town of Nipton. To make matters worse, there have been no travelers from Nipton as of late. Ghost contracts you to investigate the disturbance.

Detailed walkthrough
Upon approaching the town, you are greeted by an ecstatic (if not manic) Powder Ganger who proclaims life is grand after winning the lottery. Further exploration into town reveals a row of crucified Powder Gangers along the street. At the entrance to the town hall you'll encounter a contingent of Caesar's Legion, led by Vulpes Inculta. After a brief exchange, the Legion spares your life in order for you to spread the word of their atrocities across the wasteland. That is, provided you are not accompanied by Boone and/or dressed as NCR. If that is the case the Legion troops will attack you straight away. After you have dealt with them, you may enter the Town Hall, located directly behind where the exchange with Vulpes Inculta occurred. Inside you will find several enemies, along with more details about the demise of Nipton found within the Mayors office upstairs. There are also Land Mines that will blow you up if you don't notice them first.

After exploring the town to your liking, talk again with Ranger Ghost and you will complete the mission.

You can complete this quest by going to Nipton first before ever going to the Mojave Outpost. Talk to Ghost after talking to Rose in the bar and she will give you the quest, then you can complete it immediately by choosing the option that you have already been to Nipton.

Items of importance within the Town Hall:

Worn Key located immediately to the right upon entering; found on the counter of the PO box shelves. Turbo (x2) within the basement level on the coffee table. Dead prospector on second floor is only corpse within this building carrying any items of significance. Big Book of Science & Programmers Digest located on desk in Mayors Office. There is also copy of Future Weapons Today in the Shelf behind the Mayor's desk. Future Weapons Today located on bookshelf in Mayors Office. Nuka Cola Victory, and x2 10mm SMG's located in the locked room in Mayors Office.

NOTE: Killing all members of Caesar's Legion will yield little benefit. You will lose access to the quest Cold, Cold Heart and other assassination missions. Additionally your reputation with Caesars Legion will become "infamous", and there is practically no loot of value on any of the corpses. Killing all members will also not add any additional award from Ghost upon completing the quest, nor will you gain any reputation with NCR.

Bugs
If you find Vulpes Inculta later in the game (not in Nipton) and kill him, this quest will be completed even if you have never visited Nipton.