Fallout 76 quests

Quest system
In an interview with Geoff Keighley at E3, Todd Howard stated that the quests will be akin to found-world quests. Per Jeff Gardiner, quests will be largely received through holotapes, terminals and notes. Howard also stated in an IGN interview that robots will be utilised to deliver the story of the quest and other traditional roles played by NPCs in past iterations.

Main quests

 * Reclamation Day
 * First Contact
 * Thirst Things First
 * Second Helpings
 * Final Departure
 * An Ounce of Prevention
 * Signal Strength
 * Death from Above!

Side quests

 * Back to Basic
 * Bureau of Tourism
 * Claim Workshop at Gorge Junkyard
 * Claim Workshop at Poseidon Energy Plant Yard
 * Cold Case
 * Hunter/Hunted
 * Into the Mystery
 * Overseer's Mission
 * Personal Matters
 * Request Government Air Drop
 * Tentative Plans

Repeatable quests
Fallout 76 features repeatable quests known as events.