Vault 106

Vault 106 is one of the Vault-Tec Vaults. As part of the Vault Experiment, psychoactive drugs were released into the air filtration system 10 days after the door was sealed. Like Vault 101, this Vault is located in the Capital Wasteland and, 200 years after the Great War, in 2277, it appears to be rusted and filled with water.

The facility is run down and appears to be abandoned, although there a few residents still inside. Those that remain are insane, as it seems the drugs are still being pumped through the vault, as evidenced by the player's vision suddenly being shaded blue and reality shifting. Although the experience can be unnerving and the vault is dangerous, some of the altered-state experiences are entertaining. For instance, one of the inhabitants can be seen chasing your father and the player can have a conversation with himself on the computers. Accessing the computer terminals also reveals the Vault 106 Overseer knew the inhabitants would be fodder for drug testing and instructed security personnel to tell those in the vault everything was fine.

Appearances in games
This Vault was first mentioned in Fallout Bible and appears in Fallout 3.

Loot
This Vault also houses the Science Bobblehead.

Also a book of Tumblers Today on the Lab level and a book Nikola Tesla and You in one of the wooden boxes in the classroom in the Living Quarters.

The Overseer's computer requires a Science of 100 to hack.

In the science lab there is a mini nuke in the last chamber. There is also a hidden vault 106 master key hidden, it is not pickable unless you use the tlc command in console and go as near as possible of the item. (one with the regular "Survivor" guarding it, not an "Insane Survivor")