Vault 106

Vault 106 is one of the Vault-Tec Vaults. It is located south-south-east of Arefu and directly south of Kaelyn's Bed & Breakfast. As part of the Vault Experiment, psychoactive drugs were released into the air filtration system 10 days after the door was sealed. Like Vault 101, this Vault is located in the Capital Wasteland and in 2277, it is mostly destroyed and flooded. For some odd reason, there are still insane survivours inside, with no plausible reason for their existence given (unless they are the Lone Wanderer's hallucination, but this explanation raises the question of where the loot comes from).

It also seems the drugs are still being pumped through the vault, as evidenced by the player's vision suddenly being shaded blue and reality shifting. Although the experience can be unnerving and the vault is dangerous, some of the altered-state experiences are entertaining. For instance, one of the inhabitants can be seen chasing your father and the player can have a conversation with himself on the computers. Accessing the computer terminals also reveals the Vault 106 Overseer knew the inhabitants would be fodder for drug testing and instructed security personnel to tell those in the vault everything was fine.

A Security terminal near the entrance to the Vault doesn't require a science level, and contains a security notice from the Overseer. The Overseer's computer also requires a Science of 100 to hack, and reveals information about the experiments. Neither of these are necessary to read to access any area in the Vault.

Enemies
Vault 106 is inhabited by "Insane Survivors", Vault residents who have been driven insane by prolonged exposure to the Vault's hallucinogen-filled air. They wear Vault 106 Jumpsuits and wield a variety of melee weapons, such as lead pipes, knives, baseball bats, pool cues, etc. Despite not wearing armor, the Insane Survivors are slightly tougher than the average Wastelander, which can initially mildly surprise low-level player characters.

At times, the confines of Vault 106 make it hard to wield long range heavy-hitting weapons. With high enough Small Guns skill, the Silenced 10mm is the perfect weapon for quick dispatch of hostile druggies, who should be downed by a single headshot.

On the lowest level of Vault 106, at the end of the Science Lab section, there is a "Survivor", an elderly Vault resident wearing a Vault Lab Uniform and wielding a baseball bat (who oddly has the same ambient/combat voice files as a Raider). The Survivor has very high health (seemingly more than a Super Mutant Brute), and requires a lot of damage to kill. Additionally, an assortment of unusual hallucination effects will occur during the player's fight with the Survivor. After shooting the Survivor a few times, the player will undergo a hallucination where the Survivor disappears, and Butch DeLoria and the other members of the Tunnel Snakes gang from Vault 101 start to appear one by one and attack the player. After killing the hallucinations (each disappears after a single hit), the Survivor will appear again at full health and attack. After the Survivor takes some damage, yet another hallucination will occur, and the Survivor will appear to turn partially invisible (similar to the effect of a Stealth Boy). This persists until the Survivor is finally killed. Past the Survivor is a small storage room with assorted misc loot, including a few ammunition boxes and a Mini Nuke.

Loot
This Vault houses the Science Bobblehead.

A book of Nikola Tesla and You is hidden in one of the wooden boxes on the teacher's desk inside the classroom in the Living Quarters (the room to your left after you first enter the Living Quarters area).

Also, a book of Tumblers Today is on the Science Lab level, two floors down from the Science Lab level entrance, inside a large room with 2 lockers visible from the door.

Finally, there is a Mini Nuke in the final room of the Science Lab area, just past the fight with the Survivor.

There is also a hidden vault 106 master key hidden, it is not pickable unless you use the tcl command in console and go as near as possible of the item [This is incorrect, there is an access door to the security room where the key is located - after making your way through the science lab area {Different key, there's one key in the security room, and one key in the last chamber on the bottom right shelf of the shelves with the mininuke that you need to use tcl to to pick up.}]. (one with the regular "Survivor" guarding it, not an "Insane Survivor")

In the Living Quarters you can also find a Recon Armor and a Recon Armor helmet, both are located in a locker which is in the left room when you enter the Living Quarters.

Bugs
In the living quarters on the second floor there is a barricade. Behind this is a locked door (hard) that leads to another door. The game should turn blue and the vault will appear clean like 101 at this point. If you get through the door fast enough there will be an Overseer and if you attempt to talk to him the game will freeze (360 confirmed) or crash (PC); however, if you attempt to pickpocket him, the hallucination will stop (360).

Appearances in games
This Vault was first mentioned in Fallout Bible and appears in Fallout 3.