Anna Holt

 is a scientist working together with Doctor Li and Janice Kaplinski on portable fusion power and hydroponics experiments in 2277.

Background
She contributes to Project Purity until she is eventually kidnapped by the Enclave and persuaded to help them operate it. In spite of this, her tone and the way she speaks when encountered at the Raven Rock compound implies that she actually prefers the work there, at least in some manner, because of the superior technology she is allowed to use.

She also seems to truly agree with the Enclave's intentions, saying that it is the best way "to make the world a better place." It is left open whether this includes President Eden's plan. If Raven Rock is destroyed by convincing Eden to self destruct, she presumably perishes with the rest of the Enclave staff.

Appearances
Anna Holt only appears in Fallout 3.