Mini Nuke (Fallout 3)

The Mini Nuke is a tactical nuclear warhead designed for use in a shoulder-launched missile weapon. It is used as ammunition for the Fat Man and its unique variants.

Mini-Nukes are the single most expensive piece of ammunition, ranging from 250 to 400 caps a piece to buy, depending on your Barter level. They are also the single most powerful weapon in the game, doing many times more damage than any other weapon even at low Big Guns levels. These are also great decoration for your house or Tennpenny Tower suite.

Hand grenade
A hand grenade version of Mini Nuke also exists, although it can be even more dangerous to the user than the Fat Man version.

Fallout 3

 * Fat Man
 * Experimental MIRV
 * Liberty Prime (a larger version, but less effective)
 * VB-02 Vertibird

Available for Free
There are 59 total, in Fallout 3. Another is included with the Operation Anchorage DLC package and is at the bottom of this list, making for 60 total.

The most notable locations are five each at National Guard and The Preacher:
 * Abandoned Shacks: One Mini Nuke is in the eastern abandoned shack laying on the floor next to a Duck and Cover! book in this unmarked shantytown just north of Jalbert Brothers Waste Disposal.
 * Bethesda Ruins: Three; one in Office West (move some crates on the top floor near a fridge), one in Office East (near the exit to the catwalk), and one in the Underworks (in the storage room under a crate).
 * One in a truck's trailer northeast of Broadcast Tower KB5.
 * Several can be found on opponents and shelves in the dome of the Capitol.
 * Cliffside Cavern: One in the tent in the northwestern chamber, on top of a Hard locked safe.
 * One can be found in a derelict truck trailer on the road leading south from the Corvega Factory.
 * Deathclaw Sanctuary: One near the Endurance Bobblehead, inside, near the entrance.
 * One is in a Drainage Chamber near Jocko's Pop & Gas Stop.
 * Another can be found in a Drainage Chamber northeast of Broadcast Tower KT8.
 * Five Axles Rest Stop: One among the wrecked vehicles.
 * Fort Bannister Main contains one at the top of the stairs in an Average locked room.
 * Fort Constantine: two in a locked room (see You Gotta Shoot 'Em in the Head for more details).
 * Fort Independence: Two in room containing Miss Launcher.
 * GNR Building Plaza: Several Mini Nukes and a Fat Man are on the body of a fallen Brotherhood of Steel soldier.
 * Gold Ribbon Grocers, at the Jury Street Metro Station, has one mini nuke (see the Gold Ribbon Grocers article for more details).
 * One is located in the Ghoul outpost building south of Grayditch, in the back room on a shelf.
 * Hallowed Moors Cemetery: A single mini nuke inside the chapel.
 * Hamilton's Hideaway: One in the weapons cache behind a (key-required; get it from Three Dog) locked cell door.
 * One is in a Manhole near the Signal Sierra Victor transmission tower southeast of Jocko's Pop & Gas Stop.
 * Inside the Calverton church southwest of Jury Street Metro Station, east of Evergreen Mills, north of VAPL-84 Power Station.
 * La Maison Beauregard contains one.
 * One is on an inaccessible shelf near a workbench in Meresti Metro Station; shoot with a Sniper Rifle or knock off with a Grenade explosion.
 * The Roach King keeps one behind his throne, which is northeast of Minefield.
 * National Archives sub-basement in the generator room behind a Very Hard locked gate.
 * National Guard Depot: Five units found next to Experimental MIRV.
 * Oasis: One at the bottom of a pool in the caves.
 * Raider Farmhouse: One on the ground inside the farmhouse.
 * Two on the hands of the dummy on top of SatCom Array NN-03d.
 * One at a wharf to the west of SatCom Array NW-05a.
 * Super Duper Mart: One unit found on a table near a Protectron.
 * The Preacher: Find five doing this micro-quest in an alley near Seward St. Metro / Reilly's Ranger Compound
 * One is in a small "shack" under a large powerline support (also the location of the 1st Keller Family Transcript) north of the VAPL-58 Power Station.
 * VAPL-66 Power Station: One unit found on a table next to the left desk.
 * In a trailer behind the VAPL-84 Power Station is another mini nuke.
 * One present on a wooden shelf at the back of the barn just northwest of Vault 101.
 * One in the final chamber of the Science Lab level in Vault 106.
 * White House: at the top of the stairs (outside), three can be found near a Fat Man.
 * One at the outcast outpost armory after the DLC Operation: Anchorage simulation has been completed.

Available in Other Ways

 * One can be obtained by investing twice in Lucky Harith (see Canterbury Commons).
 * One is given to you by Donovan if you experience the random encounter with him in the Wasteland.
 * Flak and Shrapnel in Rivet City frequently restock with Mini Nukes, to the extent that one can add two or three of them with every visit to sell loot.
 * Moira Brown will give you one upon completion of the The Wasteland Survival Guide (quest). She tells upon giving you it that she was going to try to make a well with it, but that the mini nuke only made her nervous.
 * Herbert Dashwood's safe contains one. You can get the key through one of three ways: Kill him, pick his pocket, or reveal the fate of his lost ghoul friend, Argyle.
 * Agatha (woman from the quest Agatha's Song) will give you the key to her ammunition chest, which contains a mini nuke and a lot of other ammunition, if you complete her speech challenge, or alternately; kill her.
 * One can be obtained along with a Fatman during a random encounter during which a dead scavenger has them on his corpse.