Frenzy

Frenzy is a condition that can be inflicted upon certain creatures in Fallout 3 and Fallout: New Vegas. Robots, ants, and Enclave-controlled Deathclaws have certain body parts targetable in V.A.T.S, by skilled sharpshooters, or by explosives. If these parts are crippled, it will cause the target to disregard any friend-or-foe relations and attack everything indiscriminately. When frenzied, nearby creatures will attack the frenzied creature even before it has a chance to attack them. A message notification will inform the player if a target has been frenzied.

Robots
The following robots can be frenzied by targeting and crippling their Combat inhibitors:
 * Protectrons
 * Mister Handies
 * Mister Gutsies
 * Cerberus (via dialogue with the Robotics Expert perk).
 * Sentry bots
 * Robobrains
 * ED-E

Insects
The following insects can be frenzied by targeting and crippling their antennae or brain:
 * Giant ant
 * Fire ant
 * Bloatfly
 * Cazador
 * Giant mantis
 * The fire ants in the quest Those! will all become frenzied if either the Marigold ant queen is killed or if you activate a sonic pulse from the hatchery, breaking their connection with the ant queen.

Mutants

 * Any Enclave-controlled deathclaw can be frenzied by targeting and crippling its metal Enclave transmitter piece.
 * A deathclaw mother can be frenzied by the player killing a deathclaw baby.
 * Killing the Lakelurk king in the Camp Guardian caves will frenzy all the other Lakelurks in the area.

Turrets

 * Any automated turret can be frenzied by targeting and crippling its Targeting Chip or Lens. If the turret is controllable by a nearby terminal, the terminal will usually contain an option to remove the turret's targeting data. This also effectively frenzies them.

Humans

 * Cook-Cook will be frenzied if his pet brahmin, Queenie, is killed.
 * The Mesmetron has a 30% chance to frenzy human targets.