Northwest Seneca Station

The  is a part of the old metro system. The entrance is just north of Arefu on the opposite bank of the river. This collapsed metro station has a sewer tunnel that leads to Meresti Service Tunnel and eventually Meresti Metro Station, where The Family has their hideout.

The only accessible sections of the station are the restrooms area and Murphy's lab. The restroom area is inhabited by several Molerats and a bench near a radioactive area where a skeletal corpse lies beside a bottle of Vodka and a dose of Psycho. Additionally each restroom contains a First Aid Box and one of the sinks in men's restroom is filled with Frag Grenades. There is also a hidden Plasma Grenade in between a Knife and Large Scorched Book in the 2nd stall to the right in the men's bathroom as well. The Nuka-Cola vending machine in the washroom area may contain a Nuka-Cola Quantum. Murphy's lab appears to be a converted maintenance room or office and is inhabited by two Ghouls. Murphy himself and Barrett who Murphy describes as his "backup and assistant in case things get rough".

Murphy's laboratory
Talking to Murphy will reveal that he is producing Ultrajet as "the regular Jet isn't working on ghouls much". He is always short of one of the ingredients - Sugar Bombs - which can be sold to him after the talk (15 caps each, or 30 after a successful Speech check). This minor quest is described here. Provided with Sugar Bombs, Murphy sells Ultrajet to the PC.
 * The other two ingredients appear to be regular Jet and Abraxo Cleaner.

When asked about The Family, Murphy says "They live somewhere east of here. If you're feeling foolish, I think there's an underground way through their place deeper into the metro station here." This passage is the manhole leading to the Meresti Metro Station surrounded by radioactive barrels in one of the rooms in the back-right corner of Murphy's lab.

Loot wise, if you're good at stealing, there is a Sawed-Off Shotgun and shotgun shells on the desk beside the round table. On a metal shelf is a locked (Very Easy) First Aid Box holding some medical supplies. In the room with the bed there is a mine box holding frag mines and beside it some Rad-X. Everything mentioned, except for the mines, is owned and should only be taken if needed or by an evil person (or if you´re feeling lucky, punk).

In the men's bathroom in the station, there is a supply of 5 frag grenades in one of the sinks, as well as a plasma grenade hidden under a ruined book above one of the toilets in a stall.

Grocer
Above ground, slightly to the East of the Seneca Station is a small, run down grocery store. Inside there are a few radroaches, random food goods, including Sugar Bombs under the register, cigarette packs on the shelf behind the register, and a Stealth Boy in the Easy Safe (Stealth boy isn't necessarily always there). If for some reason your lockpick skill is too low, there's also an Easy computer terminal you can hack.

The entrance to the Grocer is a common random encounter trigger. The most common random encounter at this location seems to be a team of 3 Talon Company Mercs / Regulators, depending on your Karma.

Enclave Camp
After the The Waters of Life quest, an Enclave camp will appear on the highway overpass just west of the entrance to Northwest Seneca Station. The camp is populated by an Enclave Officer and two Enclave Soldiers, one of whom is equipped with Tesla Power Armor and a Missile Launcher.

(Xbox360) Curiously, this soldier is friendly until you approach the camp and alert the two hostile Enclave. If you can manage to stealth kill the two hostiles, the friendly soldier will remain friendly. He can even be talked to, saying "Yeah?". Your only response option is "I have to go now.", to which he responds "Bye."

Related quests

 * Blood Ties
 * Murphy's Bombing Run

Appearances
This location appears only in Fallout 3.