Vault 106

Vault 106 is one of the Vault-Tec Vaults. It is located south-south-east of Arefu and directly south of Kaelyn's Bed & Breakfast. As part of the Vault Experiment, psychoactive drugs were released into the air filtration system 10 days after the door was sealed. Like Vault 101, this Vault is located in the Capital Wasteland and in 2277, it is mostly destroyed and flooded. For some odd reason, there are still insane survivours inside, with no plausible reason for their existence given (unless they are the Lone Wanderer's hallucination, but this explanation raises the question of where the loot comes from).

It also seems the drugs are still being pumped through the vault, as evidenced by the player's vision suddenly being shaded blue and reality shifting. Although the experience can be unnerving and the vault is dangerous, some of the altered-state experiences are entertaining. For instance, one of the inhabitants can be seen chasing your father and the player can have a conversation with himself on the computers. Accessing the computer terminals also reveals the Vault 106 Overseer knew the inhabitants would be fodder for drug testing and instructed security personnel to tell those in the vault everything was fine.

A Security terminal near the entrance to the Vault doesn't require a science level, and contains a security notice from the Overseer. The Overseer's computer also requires a Science of 100 to hack, and reveals information about the experiments. Neither of these are necessary to read to access any area in the Vault.

Loot
This Vault also houses the Science Bobblehead.

Also a book of Tumblers Today on the Lab level and a book Nikola Tesla and You in one of the wooden boxes in the classroom in the Living Quarters.

In the science lab there is a mini nuke in the last chamber. There is also a hidden vault 106 master key hidden, it is not pickable unless you use the tcl command in console and go as near as possible of the item [This is incorrect, there is an access door to the security room where the key is located - after making your way through the science lab area]. (one with the regular "Survivor" guarding it, not an "Insane Survivor")

In the Living Quarters you can also find a Recon Armor and a Recon Armor helmet ,both are located in a locker which is in the left room when you enter the Living Quarters.

Bugs
In the living quarters on the second floor there is a barricade. Behind this is a locked door (hard) that leads to another door. The game should turn blue and the vault will appear clean like 101 at this point. If you get through the door fast enough there will be an Overseer and if you attempt to talk to him the game will freeze (360 confirmed) or crash (PC); however, if you attempt to pickpocket him, the hallucination will stop (360).

Appearances in games
This Vault was first mentioned in Fallout Bible and appears in Fallout 3.