Wasted on Nukashine

Wasted on Nukashine is a side quest in the Fallout 76 update Wild Appalachia.

Detailed walkthrough
To begin this quest, find one of the party posters near VTU, Morgantown, several bus stops or train stations. Alternatively, the poster can be purchased for free from the Atomic Shop and placed in a workshop or C.A.M.P. before interacting with it. The first quest marker leads to the Pi House in Fraternity Row in Morgantown, filled with corpses of students, seemingly killed while partying. Investigate the area, read Ted Dorfman's terminal, and access the entry entitled "Nukashine". Find the bottle of Nukashine on the desk next to the terminal and then drink it. Fight off the feral ghouls that spawn as party crashers for 2 minutes, and then the player character will black out and wake up in a random location.

Upon waking up, inspect the Nukashine label and solve the riddle to find the source of the Nukashine - a speakeasy near the University, located in the basement of Big Al's Tattoo Parlor. There, the player character will meet Biv E. Ridge, a drunk Robobrain that gives the first part of the Nukashine ingredients note. Go to the Eta Psi House, read Judy's terminal, and select the entry entitled "Supply Room" to get the password. Go back to the speakeasy in Big Al's Tattoo Parlor and open the supply room to find the remaining part of the note. After collecting both parts of the note, find all of the required ingredients (5 corn, 5 razorgrain, 5 wood, 2 boiled waters, 1 Nuka-Cola Quantum, 3 nuclear material). The nuclear material can be found right there in the supply room. Keep in mind the high levels of radiation emitting from the leaking radioactive barrels. Corn and razorgrain can be found at the farm just south of Big Al's, along with a water pump for the boiled water. Nuka-Cola Quantum can be found at the old Kanawha Nuka-Cola plant east of Charleston, purchased from a vendor bot if they have one in their inventory, or randomly found in a Nuka-Cola machine. If purchased from a vendor bot, Bubbles at The Whitespring Resort is the best choice as she usually has at least one Nuka-Cola Quantum in her stock alongside most of the other flavors of Nuka-Cola found in game. Finally, return to the speakeasy and use a brewing station to craft it and the Flash-Fermenter to finish it. After the Nukashine is ready, give it to Biv to complete the quest. After that, Biv can be visited daily for one of two repeatable quests to unlock additional brewing recipes and fully fermented alcohol that are not found anywhere else in-game except through brewing.