Wild Card: Change in Management

 is a quest in Fallout: New Vegas.

Quick walkthrough
Once you discover Yes Man, he will explain Benny's plan for killing Mr. House and taking over Vegas. The player will then be able to choose to continue Benny's plans and taking on this quest. You will have to head towards the Lucky 38 penthouse, locate the chamber in which Mr. House actually resides, and choose to either disable or kill him. After killing Mr. House, meet Yes Man outside The Tops casino and accompany him to Lucky 38.

Detailed walkthrough
After entering the Lucky 38 penthouse, look for a terminal on the wall near Mr. House ( you need science level 70). This terminal will allow you to unlock a hidden door leading to Mr. House's chamber. Note that, after activating the door, an alarm will sound, and the securitrons will become hostile. Behind the hidden door, there is another terminal, as well as several securitrons which will attack on sight. Activate the terminal in this room as well, to head on to the control room.

Once in the control room, there is one final terminal. Activate this terminal to release Mr. House's isolation chamber and expose him to the outside world. You can then talk to him, and decide his fate. Note that once the isolation chamber has been opened, regardless of the fate you decide for Mr. House, he will die within a year from exposure to outside contaminants.

To pass the initial terminal you can choose to either pass a Hard difficulty hack or execute an Executive Override and obtain the password to the terminal from either H&H Tool Company or the hotel in Camp Golf.

If you decide to kill Mr. House, you will receive the note A Tragedy Has Befallen All Mankind, and the quest The House Has Gone Bust! will instantly be started and failed.

The Kill or Disable Mr. House stage is complete once you either kill or disable Mr. House. This can be done before or after you speak to Yes Man the first time.

Sometimes Yes Man disappears after you kill Benny, if you leave the Benny's apartment and return later. Perhaps he leaves and goes somewhere else, so it's a good place to Save. You can tell him to meet you at Lucky 38 without incurring any faction penalties. Once you meet him in the Penthouse of the Lucky 38, where House's avatar formerly spoke to you the first time, the installation of Yes Man event is triggered. This triggers two quests, Beware the Wrath of Caesar! and Don't Tread on the Bear. This puts you on notice that working with Yes Man further will cause you to be unable to work with those factions.

You can let Yes Man wait for you at the Lucky 38 until you finish most of your other quests with the NCR and Caesar's Legion and are ready to proceed.

Bugs
XBox 360 and PS3: After disabling House the objective does not check off which prevents Yes Man from meeting you outside Lucky 38. (Double check that you have selected the option to permanently disable House from all systems on the same console used to wake him from the chamber)

PS3, Xbox 360 and PC: Securitrons may not become hostile