The Lowe-Down

The Lowe-Down is a quest in the Fallout 76 update Wild Appalachia.

Detailed walkthrough
Travel to Lewisburg and visit the Lewisburg Station, read the poster inside regarding "Sheepsquatch Ate My Brother" to start the quest. Afterwards, find the patrol car on the eastern side of town. Listen to Klein's notes, part 1 which can be found in a duffle bag in that car.

Find the "house with a flamingo in the front" just northeast of the patrol car. Investigate behind the house to find the following:
 * Klein's notes, part 2 - Holotape, next to one of the skeletons.
 * Wolf check-in #64 - Note, in a cooler behind the house with a plastic flamingo in front of it.

Travel to the monitoring station referenced in Wolf check-in #64. It is a greenhouse on the roof opposite Van Lowe Taxidermy. Pick up the following items which are in the leather bag found at the monitoring station:
 * Spare operative keycard - Deactivates the laser grid.
 * Further instructions

The 'Further instructions' note references the note 'From mom' which is found in the basement of Van Lowe Taxidermy. Travel back there.

Set the washing machine cycle to "Delicates" and set the dryer heat level to "Low Heat'. Interact with the day marked "Laundry Day" on the wall calendar near the machines and the wall of the basement will open to reveal the entrance to Calvin van Lowe's secret laboratory.

Investigate the laboratory to find the following clues:
 * C.H. Monthly, August - Note, on a shelf near a tinker's workbench.
 * Property deed - Note, on a desk surrounded by broken robots.

Then take the assembly password, which is in a tool chest near a tinker's workbench. This will unlock the assembly platform terminal.

Access the assembly platform terminal and access the "Session 4: Assaultron [SN:RX-0022CF9]" entry to retrieve the behavioral reprogramming holotape. Listen to it.

Access the assembly platform again and access the "!!! - EMERGENCY CHECK-IN !!!" entry. Downloading the coordinates to Garrahan Estate will complete the quest and begin the follow-up quest Wolf in Sheep's Clothing.